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In this episode we discuss sustainable chemistry and the replacement of critical materials like platinum group elements with guest Dr. Soumyadeep Chakrabortty from the Max-Planck-Institute for Kohlenforschung. We delve into the importance of sustainability in chemical reactions, the role of catalysis, and the development of more benign and cost-effective catalysts. Soumyadeep shares his experiences with asymmetric hydrogenation and the creation of a new ligands for pharmaceutical applications. The conversation also touches on collaboration between academia and industry and the impact of high-throughput screening and AI on future catalysis research.
00:48 The Importance of Sustainable Chemistry
04:02 Catalysis and Its Role in Chemistry
05:59 Asymmetric Hydrogenation Explained
15:45 Challenges in Replacing Precious Metals
20:31 Academia vs. Industry in Chemical Research
27:54 Future of Catalysis Research
Further reading on the topic:
- Iron‐Catalyzed trans‐Hydrostannation of Terminal Alkynes, DOI: 10.1002/anie.202514794
- A Homogeneous Nickel Catalyst for Reductive Amination of γ‐Keto Acids using Hydrogen, DOI: 10.1002/cctc.202400987
- Cobalt‐Catalyzed Asymmetric Hydrogenation: Substrate Specificity and Mechanistic Variability, DOI: 10.1002/anie.202315773
- Rh-Catalyzed Enantioselective Hydrogenation of Di- and Tri-Substituted Enamides Enabled by Easily Tunable P-Stereogenic N-Phosphinyl Phosphoramidite Ligands, DOI: 10.1021/acscatal.3c03336
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